Shopping Cart

Your shopping cart is currently empty

Climbazole

Name: Climbazole
Brand: TargetMol
SKU: T1403
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1403Cas No. 38083-17-9

Alias BAY-e 6975

Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff properties.

Climbazole

🥰Excellent

Purity: 98.23%

Catalog No. T1403Alias BAY-e 6975Cas No. 38083-17-9

Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff properties.

Pack Size	Price	USA Warehouse	Global Warehouse
500 mg	$40	In Stock	In Stock
1 g	$60	In Stock	In Stock
5 g	$145	-	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.23%

Resource Download

COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff properties.
In vitro	The MICs of Climbazole ranged from <0.06 to 1 μg/mL, with a median value of 0.06 μg/mL. Climbazole showed high in vitro and in vivo efficacy against Pityrosporum ovale, which may be a major cause of dandruff.
In vivo	The MICs of Climbazole ranged from <0.06 to 1 μg/mL, with a median value of 0.06 μg/mL. Climbazole showed high in vitro and in vivo efficacy against Pityrosporum ovale, which may be a major cause of dandruff.
Synonyms	BAY-e 6975

Chemical Properties

Molecular Weight	292.76
Formula	C₁₅H₁₇ClN₂O₂
Cas No.	38083-17-9
Smiles	C(OC1=CC=C(Cl)C=C1)(C(C(C)(C)C)=O)N2C=CN=C2
Relative Density.	1.321 g/cm3. Temperature:20 °C.;1.317 g/cm3. Temperature:20 °C.
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 55 mg/mL (187.87 mM), Sonication is recommended.

DMSO: 50 mg/mL (170.79 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.83 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	3.4158 mL	17.0788 mL	34.1577 mL	170.7884 mL
5 mM	0.6832 mL	3.4158 mL	6.8315 mL	34.1577 mL
10 mM	0.3416 mL	1.7079 mL	3.4158 mL	17.0788 mL
20 mM	0.1708 mL	0.8539 mL	1.7079 mL	8.5394 mL
50 mM	0.0683 mL	0.3416 mL	0.6832 mL	3.4158 mL
100 mM	0.0342 mL	0.1708 mL	0.3416 mL	1.7079 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc