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KDM2B-IN-2

Name: KDM2B-IN-2
Brand: TargetMol
SKU: T39389
Price: 60 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39389Cas No. 1965248-01-4

Alias KDM2B-IN-2

KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.

KDM2B-IN-2

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Purity: 98.96%

Catalog No. T39389Alias KDM2B-IN-2Cas No. 1965248-01-4

KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$60	In Stock	In Stock
5 mg	$147	In Stock	In Stock
10 mg	$228	In Stock	In Stock
25 mg	$428	In Stock	In Stock
50 mg	$639	In Stock	In Stock
100 mg	$890	In Stock	In Stock
500 mg	$1,830	-	In Stock
1 mL x 10 mM (in DMSO)	$162	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.96%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.
Targets&IC50	KDM2B:0.021 μM (IC50)
In vitro	In a KDM2B TR-FRET assay, KDM2B-IN-2 shows an IC50 of 0.021μM[1].
Synonyms	KDM2B-IN-2

Chemical Properties

Molecular Weight	430.59
Formula	C₂₁H₂₆N₄O₂S₂
Cas No.	1965248-01-4
Smiles	O=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1ccc(cc1)-c1ccsc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 28.8 mg/mL (66.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3224 mL	11.6120 mL	23.2239 mL	116.1197 mL
5 mM	0.4645 mL	2.3224 mL	4.6448 mL	23.2239 mL
10 mM	0.2322 mL	1.1612 mL	2.3224 mL	11.6120 mL
20 mM	0.1161 mL	0.5806 mL	1.1612 mL	5.8060 mL
50 mM	0.0464 mL	0.2322 mL	0.4645 mL	2.3224 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc