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KDM2B-IN-2

🥰Excellent
Catalog No. T39389Cas No. 1965248-01-4
Alias KDM2B-IN-2

KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.

KDM2B-IN-2

KDM2B-IN-2

🥰Excellent
Purity: 98.96%
Catalog No. T39389Alias KDM2B-IN-2Cas No. 1965248-01-4
KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$60In StockIn Stock
5 mg$147In StockIn Stock
10 mg$228In StockIn Stock
25 mg$428In StockIn Stock
50 mg$639In StockIn Stock
100 mg$890In StockIn Stock
500 mg$1,830-In Stock
1 mL x 10 mM (in DMSO)$162In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.96%
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Product Introduction

Bioactivity
Description
KDM2B-IN-2 is a potent histone demethylase (kdm2b) inhibitor.
Targets&IC50
KDM2B:0.021 μM (IC50)
In vitro
In a KDM2B TR-FRET assay, KDM2B-IN-2 shows an IC50 of 0.021μM[1].
SynonymsKDM2B-IN-2
Chemical Properties
Molecular Weight430.59
FormulaC21H26N4O2S2
Cas No.1965248-01-4
SmilesO=S(=O)(N1CCN=C1N1CCN(CC1)C1CCC1)c1ccc(cc1)-c1ccsc1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 28.8 mg/mL (66.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3224 mL11.6120 mL23.2239 mL116.1197 mL
5 mM0.4645 mL2.3224 mL4.6448 mL23.2239 mL
10 mM0.2322 mL1.1612 mL2.3224 mL11.6120 mL
20 mM0.1161 mL0.5806 mL1.1612 mL5.8060 mL
50 mM0.0464 mL0.2322 mL0.4645 mL2.3224 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

KDM-2B-IN-2KDM2BIN2KDM2B IN 2KDM2BHistoneDemethylaseHistone Demethylase
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