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N-dodecanoyl-L-Homoserine lactone

🥰Excellent
Catalog No. T13789Cas No. 137173-46-7
Alias C12-HSL

N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.

N-dodecanoyl-L-Homoserine lactone

N-dodecanoyl-L-Homoserine lactone

🥰Excellent
Purity: 99.86%
Catalog No. T13789Alias C12-HSLCas No. 137173-46-7
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$39In StockIn Stock
10 mg$64In StockIn Stock
25 mg$123In StockIn Stock
50 mg$228In StockIn Stock
100 mg$372In StockIn Stock
1 mL x 10 mM (in DMSO)$43In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.86%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule that impacts biofilm formation in bioreactors through acyl homoserine lactone (AHL) mediated microbial communication.
In vitro
N-dodecanoyl-L-Homoserine lactone inhibits IgE dependent and independent degranulation and mediator release from primary mast cells[1].
SynonymsC12-HSL
Chemical Properties
Molecular Weight283.41
FormulaC16H29NO3
Cas No.137173-46-7
SmilesCCCCCCCCCCCC(=O)N[C@H]1CCOC1=O
Relative Density.1.00 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (88.21 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5285 mL17.6423 mL35.2846 mL176.4229 mL
5 mM0.7057 mL3.5285 mL7.0569 mL35.2846 mL
10 mM0.3528 mL1.7642 mL3.5285 mL17.6423 mL
20 mM0.1764 mL0.8821 mL1.7642 mL8.8211 mL
50 mM0.0706 mL0.3528 mL0.7057 mL3.5285 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

N-dodecanoyl-L-Homoserine lactoneNdodecanoylLHomoserine lactoneN dodecanoyl L Homoserine lactoneInhibitorinhibit
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