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Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK
Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination PROTAC Others
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library
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CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

Highly Selective Inhibitor Library

Catalog No. L2010
  Library Compound List   Excel SDF

Highly selective inhibitors are able to specifically interact with the targeted molecule or pathway selectively with relatively little effect on other non-targeted molecules or pathway. The advantage of highly selective inhibitors over non-selective inhibitors is that they act more precisely on the target, thereby reducing interference with non-targets and reducing possible side-effects and toxicity. Highly selective inhibitors are widely used in drug development, especially in the treatment of cancer and other complex diseases, and are applied to intervene more effectively in pathological processes, improve the effectiveness of treatment, and reduce the incidence of adverse effects.

TargetMol has collected 580 highly selective inhibitors, the vast majority of which are at least a hundred times more selective relative to other targets, making the Highly Selective Inhibitor Library an effective tool for drug development.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
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Product Description

  • A collection of xunm highly selective inhibitors;
  • Covering 170 drug targets;
  • Some inhibitors have been approved by FDA;
  • Covering a variety of signaling pathways, such as ion channels; NF-κB; PI3K/Akt/mTOR signaling; MAPK and so on.
  • Diverse structure, strong biological activity, cell penetrable;
  • Detailed specifications, compound structure, target information, IC50 value, activity description, etc;
  • NMR, HPLC/LCMS and other detection techniques to ensure the correct structure, high purity of the product and to reduce false positives.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L2010)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Apoptosis (97)
Autophagy (63)
EGFR (33)
PI3K (25)
Epigenetic Reader Domain (20)
Histone Methyltransferase (20)
CDK (19)
BTK (18)
mTOR (15)
c-Met/HGFR (14)
GSK-3 (14)
Proteasome (14)
Aurora Kinase (13)
FGFR (13)
DPP-4 (12)
MEK (11)
Src (11)
HDAC (11)
Raf (11)
FLT (10)
PDGFR (10)
JAK (10)
Antibacterial (10)
VEGFR (9)
PARP (9)
Chk (8)
HIV Protease (8)
COX (8)
SGLT (8)
ERK (7)
TRP/TRPV Channel (7)
Cysteine Protease (7)
PLK (7)
Antibiotic (7)
PDE (7)
BCL (7)
PPAR (6)
ATM/ATR (6)
IκB/IKK (6)
SARS-CoV (6)
TGF-beta/Smad (6)
Histone Demethylase (6)
HER (6)
Trk receptor (6)
DNA/RNA Synthesis (6)
DNA-PK (6)
Ras (5)
PKC (5)
Ferroptosis (5)
Wnt/beta-catenin (5)
Virus Protease (5)
Serine Protease (5)
Phosphatase (5)
MMP (5)
P450 (5)
Mitophagy (5)
p38 MAPK (5)
Histone Acetyltransferase (5)
5-HT Receptor (5)
ALK (5)
c-Kit (5)
Dehydrogenase (5)
c-Fms (5)
Adrenergic Receptor (5)
Akt (4)
Lipase (4)
Sirtuin (4)
CSF-1R (4)
ROCK (4)
RIP kinase (4)
TAM Receptor (4)
MAO (4)
GPR (4)
Casein Kinase (4)
PDK (4)
Ligands for Target Protein for PROTAC (4)
FAAH (4)
PERK (4)
DUB (4)
AChR (4)
Potassium Channel (4)
Tyrosine Kinases (4)
PKA (4)
GluR (3)
Syk (3)
Influenza Virus (3)
Factor Xa (3)
STAT (3)
S1P Receptor (3)
Kinesin (3)
JNK (3)
Monoamine Oxidase (3)
MNK (3)
E1/E2/E3 Enzyme (3)
S6 Kinase (3)
Serine/threonin kinase (3)
iGluR (3)
IGF-1R (3)
Thrombin (3)
Caspase (3)
Prostaglandin Receptor (3)
HSP (3)
HCV Protease (3)
RAAS (3)
Pim (2)
Mitochondrial Metabolism (2)
cAMP (2)
Parasite (2)
Proton pump (2)
Phosphorylase (2)
Reactive Oxygen Species (2)
Cannabinoid Receptor (2)
NOS (2)
NOD-like Receptor (NLR) (2)
NADPH (2)
NOD (2)
Bcr-Abl (2)
Neurokinin receptor (2)
MAPK (2)
Endothelin Receptor (2)
Dopamine Receptor (2)
AMPK (2)
GRK (2)
transporter (2)
Glutathione Peroxidase (2)
Tie-2 (2)
CXCR (2)
HSV (2)
Hydroxylase (2)
IDO (2)
Adenosine Receptor (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
Integrase (2)
Sodium Channel (2)
DYRK (2)
Isocitrate Dehydrogenase (IDH) (2)
KSP (2)
CaMK (2)
Estrogen/progestogen Receptor (2)
LPL Receptor (2)
Estrogen Receptor/ERR (2)
LRRK2 (2)
Protease-activated Receptor (1)
Calcium Channel (1)
ACK (1)
Wee1 (1)
Progesterone Receptor (1)
Vasopressin Receptor (1)
Antifungal (1)
Telomerase (1)
Transferase (1)
BMI-1 (1)
Topoisomerase (1)
TLR (1)
PTEN (1)
BCRP (1)
SGK (1)
Reverse Transcriptase (1)
Rho (1)
ROS (1)
SIK (1)
Sigma receptor (1)
ATPase (1)
ASK (1)
Porcupine (1)
NMDAR (1)
Platelet aggregation (1)
HIF (1)
AChE (1)
IRE1 (1)
IRAK (1)
Interleukin (1)
Immunology/Inflammation related (1)
IFNAR (1)
DAPK (1)
Decarboxylase (1)
Histamine Receptor (1)
HIF/HIF Prolyl-Hydroxylase (1)
DNA (1)
LPA Receptor (1)
DNA Methyltransferase (1)
GlyT (1)
Glutaminase (1)
Glucocorticoid Receptor (1)
Galectin (1)
GABA Receptor (1)
Dynamin (1)
Fatty Acid Synthase (1)
FAK (1)
FABP (1)
Lipoxygenase (1)
MALT (1)
PKM (1)
NO Synthase (1)
Phospholipase (1)
Carbonic Anhydrase (1)
P-gp (1)
PD-1/PD-L1 (1)
CCR (1)
PAK (1)
CD73 (1)
OX Receptor (1)
cGAS (1)
Opioid Receptor (1)
Epoxide Hydrolase (1)
Mdm2 (1)
NF-κB (1)
Neuropeptide Y Receptor (1)
NAMPT (1)
Chloride channel (1)
MTH1 (1)
Monoamine Transporter (1)
MLK (1)
Complement System (1)
Microtubule Associated (1)
c-RET (1)
YAP (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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