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Cloxacillin sodium monohydrate

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Catalog No. T1031Cas No. 7081-44-9
Alias Bactopen

Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.

Cloxacillin sodium monohydrate
Other Forms of Cloxacillin sodium monohydrate:

Cloxacillin sodium monohydrate

🥰Excellent
Purity: 98.06%
Catalog No. T1031Alias BactopenCas No. 7081-44-9
Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
200 mg$30In StockIn Stock
500 mg$40In StockIn Stock
1 g$56In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.06%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Cloxacillin sodium monohydrate (Cloxacillin Sodium) is the sodium salt of cloxaclliin, a semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity.
In vivo
Prochlorperazine is showed to be able to induce antinociception in mice. prochlorperazine-treated mice show a complete integrity of motor co-ordination on the rota-rod test, normal spontaneous motility, as well as exploratory behaviour as revealed by the hole-board test. The antinociceptive effect of prochlorperazine appears to be due to the antagonism of D2 receptors since the increase of the pain threshold induced by the investigated compound is prevented by pretreatment with the D2 agonist quinpirole[1].
SynonymsBactopen
Chemical Properties
Molecular Weight475.88
FormulaC19H17ClN3NaO5S·H2O
Cas No.7081-44-9
Smiles[Na+].O.[C@H]12N([C@H](C(S2)(C)C)C(=O)[O-])C(=O)[C@H]1NC(=O)c1c(c2c(cccc2)Cl)noc1C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 50 mg/mL (105.07 mM), Sonication is recommended.
Ethanol: 24 mg/mL (50.43 mM), Sonication is recommended.
DMSO: 40 mg/mL (84.05 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.2 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO/H2O
1mg5mg10mg50mg
1 mM2.1014 mL10.5069 mL21.0137 mL105.0685 mL
5 mM0.4203 mL2.1014 mL4.2027 mL21.0137 mL
10 mM0.2101 mL1.0507 mL2.1014 mL10.5069 mL
20 mM0.1051 mL0.5253 mL1.0507 mL5.2534 mL
50 mM0.0420 mL0.2101 mL0.4203 mL2.1014 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

β-lactamase inhibitorS. aureus peritonitisRAW264.7NF-кBMAPKsHlαBacterialAntibiotic
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