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Demeclocycline hydrochloride

Name: Demeclocycline hydrochloride
Brand: TargetMol
SKU: T1400
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1400Cas No. 64-73-3

Alias Detravis, Demeclocycline HCl, Declomycin, Clortetrin

Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.

Demeclocycline hydrochloride

🥰Excellent

Purity: 99.14%

Catalog No. T1400Alias Detravis, Demeclocycline HCl, Declomycin, ClortetrinCas No. 64-73-3

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$30	In Stock	In Stock
50 mg	$43	In Stock	In Stock
100 mg	$55	In Stock	In Stock
200 mg	$67	In Stock	In Stock
500 mg	$81	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$51	In Stock	In Stock

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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.14%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.
Synonyms	Detravis, Demeclocycline HCl, Declomycin, Clortetrin

Chemical Properties

Molecular Weight	501.32
Formula	C₂₁H₂₁ClN₂O₈·HCl
Cas No.	64-73-3
Smiles	Cl.[H][C@]12C[C@@]3([H])[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C(=O)c1c(O)ccc(Cl)c1[C@H]2O
Relative Density.	no data available
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: 25 mg/mL (49.87 mM), Sonication is recommended.

DMSO: 126 mg/mL (251.34 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (7.98 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9947 mL	9.9737 mL	19.9473 mL	99.7367 mL
5 mM	0.3989 mL	1.9947 mL	3.9895 mL	19.9473 mL
10 mM	0.1995 mL	0.9974 mL	1.9947 mL	9.9737 mL
20 mM	0.0997 mL	0.4987 mL	0.9974 mL	4.9868 mL

DMSO

	1mg	5mg	10mg	50mg
50 mM	0.0399 mL	0.1995 mL	0.3989 mL	1.9947 mL
100 mM	0.0199 mL	0.0997 mL	0.1995 mL	0.9974 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc