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Sunifiram
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Catalog No. T7599Cas No. 314728-85-3
Alias DM-235
Sunifiram (DM-235) is a potent nootropic agent, known for enhancing cognitive functions, memory, and learning abilities through modulating neurotransmitter activity, particularly via the AMPA receptor.
Sunifiram
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Purity: 99.57%
Catalog No. T7599Alias DM-235Cas No. 314728-85-3
Sunifiram (DM-235) is a potent nootropic agent, known for enhancing cognitive functions, memory, and learning abilities through modulating neurotransmitter activity, particularly via the AMPA receptor.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $36 | In Stock | In Stock | |
| 25 mg | $60 | In Stock | In Stock | |
| 50 mg | $90 | In Stock | In Stock | |
| 100 mg | $133 | In Stock | In Stock | |
| 500 mg | $337 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $29 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.57%
Appearance:Solid
Color:White
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Product Introduction
Sunifiram AI Summary
Sunifiram demonstrates significant nootropic and antiamnesic activities in various animal models, particularly in reversing scopolamine-induced amnesia. It effectively improves memory and cognitive function in mouse passive avoidance tests, with a minimum effective dose (MED) of 0.001 mg/kg when administered subcutaneously. The compound also enhances entry latencies in these tests, indicating positive impacts on memory retention. Additionally, Sunifiram displays antiplasmodial activity against multiple strains of Plasmodium falciparum, suggesting potential as an antimalarial agent. It shows bioactivity in inhibiting Bloom's syndrome helicase, Acetylcholine Muscarinic M1 Receptor, AmpC Beta-Lactamase, and tyrosyl-DNA phosphodiesterase 1, along with inducing DNA re-replication in certain cancer cell lines. Furthermore, it exhibits stability in human plasma and phosphate buffer for up to 2.0 hours, with a half-life of at least 4.0 hours in Sprague-Dawley rats according to LC-MS/MS analysis..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Sunifiram (DM-235) is a potent nootropic agent, known for enhancing cognitive functions, memory, and learning abilities through modulating neurotransmitter activity, particularly via the AMPA receptor. |
| Synonyms | DM-235 |
| Molecular Weight | 246.3 |
| Formula | C14H18N2O2 |
| Cas No. | 314728-85-3 |
| Smiles | CCC(=O)N1CCN(CC1)C(=O)C1=CC=CC=C1 |
| Relative Density. | 1.154 g/cm3 at 20℃ |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 2.6 mg/mL (10.56 mM), Sonication is recommended. H2O: 50 mg/mL (203 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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