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CDK4/6-IN-8
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Catalog No. T61892Cas No. 2649120-22-7
CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 with an IC50 of 5.01 nM and CDK6 with an IC50 of 3.97 nM.
CDK4/6-IN-8
😃Good
Catalog No. T61892Cas No. 2649120-22-7
CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 with an IC50 of 5.01 nM and CDK6 with an IC50 of 3.97 nM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | 6-8 weeks | 6-8 weeks | |
| 50 mg | $1,980 | 6-8 weeks | 6-8 weeks | |
| 100 mg | $2,500 | 6-8 weeks | 6-8 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | CDK4/6-IN-8 (Compound 7p) is a selective inhibitor of CDK4 with an IC50 of 5.01 nM and CDK6 with an IC50 of 3.97 nM. |
| Targets&IC50 | CDK4:5.01 nM, CDK6:3.97 nM |
| In vitro | CDK4/6-IN-8 (Compound 7p) demonstrates anti-breast cancer activity, inhibiting MCF-7 cell viability with an IC50 of 2.8 μM over a 48-hour period at concentrations ranging from 0.1 to 656.1 μM [1]. |
| Molecular Weight | 398.37 |
| Formula | C18H18N6O5 |
| Cas No. | 2649120-22-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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