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Tribromoethyl alcohol

🥰Excellent
Catalog No. T0807Cas No. 75-80-9
Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol

Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.

Tribromoethyl alcohol

Tribromoethyl alcohol

🥰Excellent
Purity: 99.98%
Catalog No. T0807Alias Tribromoethanol, TBE, Basibrol, Avertin, 2,2,2-TribromoethanolCas No. 75-80-9
Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.
Pack SizePriceAvailabilityQuantity
1 g$30In Stock
5 g$61In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.98%
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COA GC HNMR HPLC

Product Introduction

Bioactivity
Description
Tribromoethyl alcohol (Avertin) is an organic compound used to anesthetize mice.
In vivo
Tribromoethanol has been proposed as an acceptable anaesthetic in dogs, cats, mice, rats, and gerbils. It possesses a concentration dependent irritant effect. When used at low concentration, it displays good anesthetic effect. A high dose of tribromoethanol is not a suitable anesthetic for major surgery in all mouse strains because of the risk of pathologic changes in the abdominal organs, such as retention of the digestive tract, peritonitis, and fibrinoid adhesion[1][2].
SynonymsTribromoethanol, TBE, Basibrol, Avertin, 2,2,2-Tribromoethanol
Chemical Properties
Molecular Weight282.76
FormulaC2H3Br3O
Cas No.75-80-9
SmilesC(CO)(Br)(Br)Br
Relative Density.2.866 g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 237 mg/mL (838.17 mM), Sonication is recommended.
H2O: 40 mg/mL (141.46 mM), Sonication is recommended.
Ethanol: 52 mg/mL (183.9 mM), Sonication is recommended.
Solution Preparation Table
H2O/Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.5366 mL17.6828 mL35.3657 mL176.8284 mL
5 mM0.7073 mL3.5366 mL7.0731 mL35.3657 mL
10 mM0.3537 mL1.7683 mL3.5366 mL17.6828 mL
20 mM0.1768 mL0.8841 mL1.7683 mL8.8414 mL
50 mM0.0707 mL0.3537 mL0.7073 mL3.5366 mL
100 mM0.0354 mL0.1768 mL0.3537 mL1.7683 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tribromoethyl alcoholNarcolanInhibitorinhibit
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