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(Rac)-Brassinazole

Name: (Rac)-Brassinazole
Brand: TargetMol
SKU: T7132
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: BRASSINAZOLE) Copy Product Info

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Synonyms: BRASSINAZOLE

Catalog No. T7132 Copy Product Info

Purity: 99.81%

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(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynthesis inhibitor.

Cas No. 224047-41-0

Pack Size	Price	USA Stock	Global Stock
1 mg	$54	In Stock	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$176	In Stock	In Stock
25 mg	$285	In Stock	In Stock
50 mg	$461	In Stock	In Stock
100 mg	$651	In Stock	In Stock
500 mg	$1,390	-	In Stock
1 mL x 10 mM (in DMSO)	$128	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.81%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	(Rac)-Brassinazole are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynthesis inhibitor.
In vitro	Brassinazole is a specific BR biosynthesis inhibitor. Brassinazole-treated cress also showed dwarfism, with altered leaf morphology, including the downward curling and dark green color typical of Arabidopsis BR-deficient mutants, and this dwarfism was reversed by the application of 10 nM brassinolide. This result suggests that BRs are essential for plant growth, and that brassinazole can be used to clarify the function of BRs in plants as a complement to BR-deficient mutants.
Synonyms	BRASSINAZOLE

Chemical Properties

Molecular Weight	327.81
Formula	C₁₈H₁₈ClN₃O
Cas No.	224047-41-0
Smiles	CC(O)(C(Cc1ccc(Cl)cc1)n1cncn1)c1ccccc1
Relative Density.	1.22g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 120 mg/mL (366.07 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 10 mg/mL (30.51 mM), Suspension.

10% DMSO+90% Corn Oil: 0.5 mg/mL (1.53 mM), Sonication is recommended.

10% DMSO+90% Corn oil: < 10 mg/mL (30.51 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

10% DMSO+90% Saline: < 10 mg/mL (30.51 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

10% DMSO+90% (20% SBE-β-CD in Saline): < 10 mg/mL (30.51 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0505 mL	15.2527 mL	30.5055 mL	152.5274 mL
5 mM	0.6101 mL	3.0505 mL	6.1011 mL	30.5055 mL
10 mM	0.3051 mL	1.5253 mL	3.0505 mL	15.2527 mL
20 mM	0.1525 mL	0.7626 mL	1.5253 mL	7.6264 mL
50 mM	0.0610 mL	0.3051 mL	0.6101 mL	3.0505 mL
100 mM	0.0305 mL	0.1525 mL	0.3051 mL	1.5253 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc