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4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity. 4SC-203 exhibits unique selectivity for Flt3, Flt3 mutants, Axl, Alk, Fak, VEGF-R2, and Trk receptors in the low nM range.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $68 | In Stock | In Stock | |
| 5 mg | $163 | In Stock | In Stock | |
| 10 mg | $263 | In Stock | In Stock | |
| 25 mg | $463 | In Stock | In Stock | |
| 50 mg | $653 | In Stock | In Stock | |
| 100 mg | $928 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $226 | In Stock | In Stock |
| Description | 4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity. 4SC-203 exhibits unique selectivity for Flt3, Flt3 mutants, Axl, Alk, Fak, VEGF-R2, and Trk receptors in the low nM range. |
| In vitro | 4SC-203 exhibits unique selectivity in the low nM range for Flt3, Flt3 mutants, Axl, Alk, Fak, VEGF-R2, and Trk receptors.[1] |
| In vivo | In preclinical studies, 4SC-203 demonstrated significant antitumor activity in in vivo models relevant to acute myeloid leukemia. In a first-in-human study in healthy volunteers, 4SC-203 was shown to be well tolerated across the concentration range studied and to have a favorable pharmacokinetic profile.[1] |
| Molecular Weight | 642.77 |
| Formula | C33H38N8O4S |
| Cas No. | 895533-09-2 |
| Smiles | COc1ccc(C)cc1NC(=O)Nc1nc2ccc(Nc3ncnc4cc(OCCCN5CCN(C)CC5)c(OC)cc34)cc2s1 |
| Relative Density. | 1.341 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: Slightly soluble |
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