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SR15006

Name: SR15006
Brand: TargetMol
SKU: T60037
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60037Cas No. 2505001-54-5

SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).

SR15006

🥰Excellent

Purity: 99.87%

Catalog No. T60037Cas No. 2505001-54-5

SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).

Pack Size	Price	Availability
10 mg	$41	In Stock
25 mg	$83	In Stock
50 mg	$156	In Stock
100 mg	$233	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Batch Information

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Purity:99.87%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).
In vitro	In DLD-1 CRC cells, SR15006 (1 μM or 10 μM) causes a significant reduction in the levels of tested cyclins over the course of 72 hours[1].

Chemical Properties

Molecular Weight	385.87
Formula	C₁₆H₂₀ClN₃O₄S
Cas No.	2505001-54-5
Smiles	CS(=O)(=O)N1CCN(CC1)C(=O)CNC(=O)\C=C\c1cccc(Cl)c1
Relative Density.	1.41 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (246.20 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5915 mL	12.9577 mL	25.9155 mL	129.5773 mL
5 mM	0.5183 mL	2.5915 mL	5.1831 mL	25.9155 mL
10 mM	0.2592 mL	1.2958 mL	2.5915 mL	12.9577 mL
20 mM	0.1296 mL	0.6479 mL	1.2958 mL	6.4789 mL
50 mM	0.0518 mL	0.2592 mL	0.5183 mL	2.5915 mL
100 mM	0.0259 mL	0.1296 mL	0.2592 mL	1.2958 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc