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4-Butylresorcinol

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Catalog No. T7125Cas No. 18979-61-8
Alias Butylresorcinol

4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.

4-Butylresorcinol

4-Butylresorcinol

😃Good
Purity: 98.64%
Catalog No. T7125Alias ButylresorcinolCas No. 18979-61-8
4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
Pack SizePriceAvailabilityQuantity
100 mg$34In Stock
500 mg$80Backorder
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:98.64%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.
Targets&IC50
Tyrosinase:11.27 μM
In vitro
4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. It is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression.
SynonymsButylresorcinol
Chemical Properties
Molecular Weight166.22
FormulaC10H14O2
Cas No.18979-61-8
SmilesCCCCc1ccc(O)cc1O
Relative Density.Ca. 1.04 g/cm3. Temperature:25 °C.
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 150 mg/mL (902.42 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.0161 mL30.0806 mL60.1612 mL300.8062 mL
5 mM1.2032 mL6.0161 mL12.0322 mL60.1612 mL
10 mM0.6016 mL3.0081 mL6.0161 mL30.0806 mL
20 mM0.3008 mL1.5040 mL3.0081 mL15.0403 mL
50 mM0.1203 mL0.6016 mL1.2032 mL6.0161 mL
100 mM0.0602 mL0.3008 mL0.6016 mL3.0081 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tyrosinase4-Butylresorcinol4Butylresorcinol4 Butylresorcinol
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