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FHD-286

Name: FHD-286
Brand: TargetMol
SKU: T9749
Price: 148 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9749Cas No. 2671128-05-3

FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.

FHD-286

🥰Excellent

Purity: 99.73%

Catalog No. T9749Cas No. 2671128-05-3

FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.

Pack Size	Price	Availability
1 mg	$148	In Stock
5 mg	$372	In Stock
10 mg	$578	In Stock
25 mg	$787	In Stock
50 mg	$987	In Stock
100 mg	$1,360	In Stock
500 mg	$2,730	In Stock
1 mL x 10 mM (in DMSO)	$397	In Stock

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Purity:99.73%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description

FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.

Chemical Properties

Molecular Weight	562.66
Formula	C₂₄H₃₀N₆O₆S₂
Cas No.	2671128-05-3
Smiles	COC[C@H](NC(=O)c1ccn(c1)S(C)(=O)=O)C(=O)Nc1nc(cs1)-c1cccc(n1)N1C[C@H](C)O[C@H](C)C1
Relative Density.	1.46 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 245 mg/mL (435.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7773 mL	8.8864 mL	17.7727 mL	88.8636 mL
5 mM	0.3555 mL	1.7773 mL	3.5545 mL	17.7727 mL
10 mM	0.1777 mL	0.8886 mL	1.7773 mL	8.8864 mL
20 mM	0.0889 mL	0.4443 mL	0.8886 mL	4.4432 mL
50 mM	0.0355 mL	0.1777 mL	0.3555 mL	1.7773 mL
100 mM	0.0178 mL	0.0889 mL	0.1777 mL	0.8886 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc