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LDC4297

Name: LDC4297
Brand: TargetMol
SKU: T4051
Price: 49 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T4051Cas No. 1453834-21-3

Alias LDC044297

LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.

LDC4297

🥰Excellent

Purity: 98.25%

Catalog No. T4051Alias LDC044297Cas No. 1453834-21-3

LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.

Pack Size	Price	Availability	Quantity
1 mg	$49	In Stock

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Batch Information

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Purity:98.25%

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description	LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.
Targets&IC50	HSV1:0.02 μM (EC50), CDK7:0.13 nM, HSV2:0.27 μM (EC50)
Synonyms	LDC044297

Chemical Properties

Molecular Weight	432.52
Formula	C₂₃H₂₈N₈O
Cas No.	1453834-21-3
Smiles	CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12
Relative Density.	1.37 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (138.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3120 mL	11.5602 mL	23.1203 mL	115.6016 mL
5 mM	0.4624 mL	2.3120 mL	4.6241 mL	23.1203 mL
10 mM	0.2312 mL	1.1560 mL	2.3120 mL	11.5602 mL
20 mM	0.1156 mL	0.5780 mL	1.1560 mL	5.7801 mL
50 mM	0.0462 mL	0.2312 mL	0.4624 mL	2.3120 mL
100 mM	0.0231 mL	0.1156 mL	0.2312 mL	1.1560 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc