IRE1α kinase-IN-6

Name: IRE1α kinase-IN-6
Brand: TargetMol
SKU: T40336
Rating: 4.5 (1 reviews)

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Catalog No. T40336Cas No. 2715123-88-7

Alias IRE1α kinase-IN-6

IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.

IRE1α kinase-IN-6

😃Good

Catalog No. T40336Alias IRE1α kinase-IN-6Cas No. 2715123-88-7

IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.

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Product Introduction

Bioactivity

Description	IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.
Synonyms	IRE1α kinase-IN-6

Chemical Properties

Molecular Weight	609.52
Formula	C₂₅H₂₃Cl₂FN₆O₃S₂
Cas No.	2715123-88-7
Smiles	N[C@H]1CC[C@@H](CC1)Nc1ncnc2c(csc12)C(=O)Nc1c(Cl)ccc(NS(=O)(=O)c2ccccc2Cl)c1F \|wU:4.7,wD:1.0,(-4,-5.39,;-2.67,-4.62,;-1.33,-5.39,;,-4.62,;,-3.08,;-1.33,-2.31,;-2.67,-3.08,;1.33,-2.31,;1.33,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;,1.54,;-1.46,2.02,;-2.37,.77,;-1.46,-.48,;;-1.94,3.48,;-.91,4.63,;-3.45,3.8,;-3.92,5.27,;-2.89,6.41,;-1.39,6.09,;-3.37,7.87,;-4.87,8.19,;-5.91,7.05,;-7.41,7.37,;-7.89,8.83,;-9.35,8.36,;-6.42,9.31,;-8.36,10.3,;-7.33,11.44,;-7.81,12.91,;-9.31,13.23,;-10.35,12.08,;-9.87,10.62,;-10.9,9.48,;-5.43,5.59,;-6.46,4.44,)\|

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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