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Silydianin

Name: Silydianin
Brand: TargetMol
SKU: T3880
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T3880Cas No. 29782-68-1

Alias Silidianin

Silydianin (Silidianin) exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exerts inhibition of OATP2B1 (unknown origin) expressed in MDCK2 cells.

Silydianin

🥰Excellent

Purity: 98.56%

Catalog No. T3880Alias SilidianinCas No. 29782-68-1

Pack Size	Price	Availability
1 mg	$39	In Stock
5 mg	$97	In Stock
10 mg	$143	In Stock
25 mg	$238	In Stock
50 mg	$358	In Stock
100 mg	$528	In Stock
1 mL x 10 mM (in DMSO)	$97	In Stock

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Batch Information

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Purity:98.56%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Silydianin (Silidianin) exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exerts inhibition of OATP2B1 (unknown origin) expressed in MDCK2 cells.
Synonyms	Silidianin

Chemical Properties

Molecular Weight	482.44
Formula	C₂₅H₂₂O₁₀
Cas No.	29782-68-1
Smiles	COc1cc(ccc1O)[C@@H]1[C@H]2CO[C@]3(O)[C@H]2C(=C[C@H]1C3=O)[C@H]1Oc2cc(O)cc(O)c2C(=O)[C@@H]1O
Relative Density.	1.676g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (134.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0728 mL	10.3640 mL	20.7280 mL	103.6398 mL
5 mM	0.4146 mL	2.0728 mL	4.1456 mL	20.7280 mL
10 mM	0.2073 mL	1.0364 mL	2.0728 mL	10.3640 mL
20 mM	0.1036 mL	0.5182 mL	1.0364 mL	5.1820 mL
50 mM	0.0415 mL	0.2073 mL	0.4146 mL	2.0728 mL
100 mM	0.0207 mL	0.1036 mL	0.2073 mL	1.0364 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc