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Ethacridine lactate

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Catalog No. T5967Cas No. 1837-57-6
Alias Acrinol, 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE

Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.

Ethacridine lactate
Other Forms of Ethacridine lactate:

Ethacridine lactate

🥰Excellent
Purity: 99.64%
Catalog No. T5967Alias Acrinol, 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATECas No. 1837-57-6
Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$31-In Stock
500 mg$64-In Stock
1 g$91-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.64%
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COA LCMS HNMR HPLC

Product Introduction

Bioactivity
Description
Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
In vitro
Ethacridine Lactate is a safe abortifacient with about 80% success and hardly any side effects[1].
SynonymsAcrinol, 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE
Chemical Properties
Molecular Weight343.38
FormulaC18H21N3O4
Cas No.1837-57-6
SmilesCC(O)C(O)=O.CCOc1ccc2nc3cc(N)ccc3c(N)c2c1
Relative Density.1.2764 g/cm3 (Estimated)
ColorYellow
AppearanceSolid
Storage & Solubility Information
Storagestore under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (291.22 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (11.65 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9122 mL14.5611 mL29.1223 mL145.6113 mL
5 mM0.5824 mL2.9122 mL5.8245 mL29.1223 mL
10 mM0.2912 mL1.4561 mL2.9122 mL14.5611 mL
20 mM0.1456 mL0.7281 mL1.4561 mL7.2806 mL
50 mM0.0582 mL0.2912 mL0.5824 mL2.9122 mL
100 mM0.0291 mL0.1456 mL0.2912 mL1.4561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

StaphylococcusPARGInhibitorinhibitgram-positiveEthacridine lactateEthacridine LactateEthacridinecocciBacterialaureusantisepticabortifacient6,9-DIAMINO-2-ETHOXYACRIDINE Lactate
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