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Anti-Mouse CTLA-4 Antibody (9D9)
🥰Excellent
Catalog No. T78261
Anti-Mouse CTLA-4 Antibody (9D9) is an IgG2b monoclonal antibody that binds CTLA-4, blocking B7 interaction. It enhances T cell function by modulating CD8+/Treg ratios and is used in colon cancer and melanoma research.
Anti-Mouse CTLA-4 Antibody (9D9)
Anti-Mouse CTLA-4 Antibody (9D9)
🥰Excellent
Purity: 95%
Catalog No. T78261
Anti-Mouse CTLA-4 Antibody (9D9) is an IgG2b monoclonal antibody that binds CTLA-4, blocking B7 interaction. It enhances T cell function by modulating CD8+/Treg ratios and is used in colon cancer and melanoma research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $129 | In Stock | |
| 5 mg | $413 | In Stock | |
| 10 mg | $662 | In Stock | |
| 25 mg | $987 | In Stock | |
| 50 mg | $1,370 | In Stock |
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Concentration:13.32 mg/mL
Purity:95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Anti-Mouse CTLA-4 Antibody (9D9) is an IgG2b monoclonal antibody that binds CTLA-4, blocking B7 interaction. It enhances T cell function by modulating CD8+/Treg ratios and is used in colon cancer and melanoma research. |
| In vitro | Anti-Mouse CTLA-4 Antibody (9D9) (0.01-1000 nM, 1 hour) treatment of HEK293-F cells can significantly block the binding of B7 to CTLA-4 in HEK293-F cells (ELISA IC50 value is 23.5 nM, cell surface IC50 value is 24.4 nM). [1] |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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