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Anti-Mouse CTLA-4 Antibody (9D9) is an IgG2b monoclonal antibody that binds CTLA-4, blocking B7 interaction. It enhances T cell function by modulating CD8+/Treg ratios and is used in colon cancer and melanoma research.

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $129 | - | In Stock | |
| 5 mg | $413 | - | In Stock | |
| 10 mg | $662 | - | In Stock | |
| 25 mg | $987 | - | In Stock | |
| 50 mg | $1,370 | - | In Stock |
| Description | Anti-Mouse CTLA-4 Antibody (9D9) is an IgG2b monoclonal antibody that binds CTLA-4, blocking B7 interaction. It enhances T cell function by modulating CD8+/Treg ratios and is used in colon cancer and melanoma research. |
| In vitro | Anti-Mouse CTLA-4 Antibody (9D9) (0.01-1000 nM, 1 hour) treatment of HEK293-F cells can significantly block the binding of B7 to CTLA-4 in HEK293-F cells (ELISA IC50 value is 23.5 nM, cell surface IC50 value is 24.4 nM). [1] |
| Clone | 9D9 |
| Reactivity | Mouse |
| Verified Activity | Immobilized Mouse CTLA-4 Protein (His) (TMPY-01604) at 1 μg/mL (100 μL/well) can bind Anti-Mouse CTLA-4 Antibody (9D9). The EC50 is 1.86 ng/mL. ![]() |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | CTLA-4/CD152 |
| Molecular Weight | 150 kDa |
| Isotype | Mouse IgG2b kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature | Shipping with blue ice/Shipping at ambient temperature. |
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