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Quinidine

Name: Quinidine
Brand: TargetMol
SKU: T7938
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7938Cas No. 56-54-2

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Quinidine

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Purity: 99.99%

Catalog No. T7938Cas No. 56-54-2

Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$30	-	In Stock
100 mg	$42	Backorder	Backorder
200 mg	$55	Backorder	Backorder
1 mL x 10 mM (in DMSO)	$39	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.99%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.
In vitro	Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent manner.It decreases the amplitude and duration of action potentials in isolated canine ventricular myocytes[1].

Chemical Properties

Molecular Weight	324.42
Formula	C₂₀H₂₄N₂O₂
Cas No.	56-54-2
Smiles	[H][C@@]12CCN(C[C@@H]1C=C)[C@H](C2)[C@@H](O)c1ccnc2ccc(OC)cc12
Relative Density.	1.1294 g/cm3 (Estimated)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (154.12 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.16 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0824 mL	15.4121 mL	30.8242 mL	154.1212 mL
5 mM	0.6165 mL	3.0824 mL	6.1648 mL	30.8242 mL
10 mM	0.3082 mL	1.5412 mL	3.0824 mL	15.4121 mL
20 mM	0.1541 mL	0.7706 mL	1.5412 mL	7.7061 mL
50 mM	0.0616 mL	0.3082 mL	0.6165 mL	3.0824 mL
100 mM	0.0308 mL	0.1541 mL	0.3082 mL	1.5412 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc