CCT241533 dihydrochloride

Name: CCT241533 dihydrochloride
Brand: TargetMol
SKU: T36704
Rating: 4.5 (1 reviews)

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Catalog No. T36704Cas No. 1962925-28-5

Alias CCT 241533 dihydrochloride

Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.

CCT241533 dihydrochloride

😃Good

Catalog No. T36704Alias CCT 241533 dihydrochlorideCas No. 1962925-28-5

Pack Size	Price	Availability	Quantity
10 mg	$1,420	35 days

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Product Introduction

Bioactivity

Description	Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radiation-induced apoptosis of mouse thymocytes.
Targets&IC50	Chk1:245 nM (IC50), Chk2:1.16 nM (Ki), Chk2:3 nM (IC50)
Synonyms	CCT 241533 dihydrochloride

Chemical Properties

Molecular Weight	515.41
Formula	C₂₃H₂₉Cl₂FN₄O₄
Cas No.	1962925-28-5

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO: Soluble

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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