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DX600 TFA

Name: DX600 TFA
Brand: TargetMol
SKU: TP1622
Price: 163 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TP1622

DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.

DX600 TFA

🥰Excellent

Purity: 99.54%

Catalog No. TP1622

DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.

Pack Size	Price	Availability
1 mg	$163	In Stock
2 mg	$243	In Stock
5 mg	$413	In Stock
10 mg	$618	In Stock
25 mg	$985	In Stock
50 mg	$1,330	In Stock
100 mg	$1,790	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.54%

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description

DX600 TFA is a specific inhibitor of ACE2 and does not cross-react with ACE.

Chemical Properties

Molecular Weight	2841.01
Formula	C₁₂₃H₁₆₉F₃N₃₂O₃₉S₂
Smiles	OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](CS)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(C)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)NCC(=O)NCC(N)=O
Relative Density.	no data available
Sequence	Ac-{Gly}{Asp}{Tyr}{Ser}{His}{Cys}{Ser}{Pro}{Leu}{Arg}{Tyr}{Pro}{Trp}{Lys}{Cys}{Thr}{Tyr}{Pro}{Asp}{Pro}{Glu}{Gly}{Gly}{Gly}-Nh2
Sequence Short	Ac-GDYSHCSPLRYPWKCTYPDPEGGG-NH2

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.3520 mL	1.7599 mL	3.5199 mL	17.5994 mL
5 mM	0.0704 mL	0.3520 mL	0.7040 mL	3.5199 mL
10 mM	0.0352 mL	0.1760 mL	0.3520 mL	1.7599 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc