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KD-027

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Catalog No. T27720Cas No. 906421-01-0
Alias SLx-2101, SLx2101, KD027

KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.

KD-027

KD-027

😃Good
Catalog No. T27720Alias SLx-2101, SLx2101, KD027Cas No. 906421-01-0
KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$2936-8 weeks6-8 weeks
5 mg$7226-8 weeks6-8 weeks
10 mg$9876-8 weeks6-8 weeks
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
KD-027 is a novel and long-acting PDE5A(phosphodiesterase 5A) inhibitor with potential antihypertensive activity.
SynonymsSLx-2101, SLx2101, KD027
Chemical Properties
Molecular Weight561.65
FormulaC25H35N7O6S
Cas No.906421-01-0
SmilesO=C1N=C(NN2C1=C(N=C2CCC)C)C=3C=C(C=CC3OCC)S(=O)(=O)N(C)CC(=O)N(C)CC(=O)N(C)C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 250 mg/mL (445.12 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7805 mL8.9023 mL17.8047 mL89.0234 mL
5 mM0.3561 mL1.7805 mL3.5609 mL17.8047 mL
10 mM0.1780 mL0.8902 mL1.7805 mL8.9023 mL
20 mM0.0890 mL0.4451 mL0.8902 mL4.4512 mL
50 mM0.0356 mL0.1780 mL0.3561 mL1.7805 mL
100 mM0.0178 mL0.0890 mL0.1780 mL0.8902 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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