Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity that induces DNA fragmentation for the study of neoplasms, immune disorders, and lymphatic disorders.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 108.00 | |
10 mg | In stock | $ 162.00 | |
25 mg | In stock | $ 268.00 | |
50 mg | In stock | $ 392.00 | |
100 mg | In stock | $ 668.00 | |
500 mg | In stock | $ 2,530.00 | |
1 g | 6-8 weeks | $ 3,870.00 |
Description | Daniquidone (Batracylin) is a potent dual inhibitor of DNA topoisomerase I and DNA topoisomerase II with cytotoxic and antiproliferative activity that induces DNA fragmentation for the study of neoplasms, immune disorders, and lymphatic disorders. |
Targets&IC50 | HT29 cells:10.02 µM |
In vitro | Daniquidone (0-300 µM; 6 hours) exhibits cytotoxicity against HT29 cells, with an IC50 value of 10.02 µM[1]. Additionally, Daniquidone (100, 300 µM;3 hours) can induce protein-linked DNA breaks consistent with topoisomerase targeting[1]. |
Synonyms | NSC 320846, BAY-H 2049 |
Molecular Weight | 249.27 |
Formula | C15H11N3O |
CAS No. | 67199-66-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Daniquidone 67199-66-0 DNA Damage/DNA Repair Topoisomerase NSC 320846 BAY-H 2049 inhibitor inhibit