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DNQX

Name: DNQX
Brand: TargetMol
SKU: T7304
Price: 50 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7304Cas No. 2379-57-9

Alias FG 9041

DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

DNQX

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Purity: 99.1%

Catalog No. T7304Alias FG 9041Cas No. 2379-57-9

DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)

Pack Size	Price	Availability
25 mg	$51	In Stock
50 mg	$82	In Stock
100 mg	$117	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Purity:99.1%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)
In vitro	DNQX has been used to specifically target AMPA and kainate receptor responses and thus differentiate from that of NMDA receptors. DNQX does not stimulate a robust long-term potentiation in the hippocampus[1]
Synonyms	FG 9041

Chemical Properties

Molecular Weight	252.14
Formula	C₈H₄N₄O₆
Cas No.	2379-57-9
Smiles	[O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1[N+]([O-])=O
Relative Density.	1.738 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (237.96 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.93 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9661 mL	19.8303 mL	39.6605 mL	198.3025 mL
5 mM	0.7932 mL	3.9661 mL	7.9321 mL	39.6605 mL
10 mM	0.3966 mL	1.9830 mL	3.9661 mL	19.8303 mL
20 mM	0.1983 mL	0.9915 mL	1.9830 mL	9.9151 mL
50 mM	0.0793 mL	0.3966 mL	0.7932 mL	3.9661 mL
100 mM	0.0397 mL	0.1983 mL	0.3966 mL	1.9830 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc