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Carbenoxolone disodium

🥰Excellent
Catalog No. T0992Cas No. 7421-40-1
Alias Duogastrone, Bioral, Biogastrone

Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.

Carbenoxolone disodium
Other Forms of Carbenoxolone disodium:
CarbenoxoloneT77325697-56-3
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Carbenoxolone disodium

🥰Excellent
Purity: 99.69%
Catalog No. T0992Alias Duogastrone, Bioral, BiogastroneCas No. 7421-40-1
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.
Pack SizePriceAvailabilityQuantity
10 mg$30In Stock
25 mg$64In Stock
50 mg$97In Stock
100 mg$163In Stock
500 mg$397In Stock
1 mL x 10 mM (in DMSO)$57In Stock
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Purity:99.69%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.
SynonymsDuogastrone, Bioral, Biogastrone
Chemical Properties
Molecular Weight614.72
FormulaC34H48Na2O7
Cas No.7421-40-1
Smiles[Na+].[Na+].CC1(C)C(CCC2(C)C1CCC1(C)C2C(=O)C=C2C3CC(C)(CCC3(C)CCC12C)C([O-])=O)OC(=O)CCC([O-])=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 162.7 mM, Sonication is recommended.
DMSO: 13.75 mg/mL (22.37 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.63 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM1.6268 mL8.1338 mL16.2676 mL81.3378 mL
5 mM0.3254 mL1.6268 mL3.2535 mL16.2676 mL
10 mM0.1627 mL0.8134 mL1.6268 mL8.1338 mL
20 mM0.0813 mL0.4067 mL0.8134 mL4.0669 mL
H2O
1mg5mg10mg50mg
50 mM0.0325 mL0.1627 mL0.3254 mL1.6268 mL
100 mM0.0163 mL0.0813 mL0.1627 mL0.8134 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

VACVVaccinia viruspepticOrthopoxvirusoral ulcerationmuscle relaxantInhibitorinhibitinflammation,?creamhypnoticglycyrrhetinicGapJunctionProteinGap Junction ProteinesophagealderivativeCarbenoxolone disodiumCarbenoxoloneacid?anticonvulsant
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