Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BS-181 dihydrochloride is a selective and potent inhibitor of CDK7 with an IC50 value of 21 nM. BS-181 dihydrochloride inhibits CDK2 (IC50: 880 nM), CDK5 (IC50: 3000 nM) and CDK9 (IC50: 4200 nM), but does not block CDK1, 4 and 6. BS-181 dihydrochloride inhibits the growth of a group of cancer cells (IC50: 11.5 μM-37.3 μM) and induces apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | 35 days | $ 588.00 | |
50 mg | 35 days | $ 2,510.00 |
Description | BS-181 dihydrochloride is a selective and potent inhibitor of CDK7 with an IC50 value of 21 nM. BS-181 dihydrochloride inhibits CDK2 (IC50: 880 nM), CDK5 (IC50: 3000 nM) and CDK9 (IC50: 4200 nM), but does not block CDK1, 4 and 6. BS-181 dihydrochloride inhibits the growth of a group of cancer cells (IC50: 11.5 μM-37.3 μM) and induces apoptosis. |
Molecular Weight | 453.46 |
Formula | C22H34Cl2N6 |
CAS No. | 1883548-83-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BS-181 dihydrochloride 1883548-83-1 inhibitor inhibit