Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism. It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 916.00 | |
50 mg | 6-8 weeks | $ 1,190.00 | |
100 mg | 6-8 weeks | $ 1,910.00 |
Description | GK187 is an inhibitor of Group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2), an enzyme involved in basal cell metabolism. It inhibits GVIA iPLA2 by 99.8% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA cPLA2 and GV sPLA2 where it shows less than 25% and 32.8% inhibition, respectively. |
Molecular Weight | 310.26 |
Formula | C14H15F5O2 |
CAS No. | 1071001-50-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 10 mg/mL
DMSO: 10 mg/mL
Ethanol:PBS (pH 7.2) (1:2): 0.3 mg/mL
DMF: 10 mg/mL
You can also refer to dose conversion for different animals. More
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GK187 1071001-50-7 GK 187 GK-187 inhibitor inhibit