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Vortioxetine

Name: Vortioxetine
Brand: TargetMol
SKU: T2395
Price: 40 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2395Cas No. 508233-74-7

Alias Lu AA 21004

Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.

Vortioxetine

🥰Excellent

Purity: 99.34%

Catalog No. T2395Alias Lu AA 21004Cas No. 508233-74-7

Pack Size	Price	Availability
10 mg	$43	In Stock
25 mg	$63	In Stock
50 mg	$87	In Stock
100 mg	$126	In Stock
200 mg	$226	In Stock
500 mg	$369	In Stock
1 g	$531	In Stock
1 mL x 10 mM (in DMSO)	$40	In Stock

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Batch Information

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Purity:99.34%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
Targets&IC50	5-HT1B:33 nM (Ki), SERT:1.6 nM (Ki), 5-HT3A:3.7 nM (Ki), 5-HT7:19 nM (Ki), 5-HT1A:15 nM (Ki)
Synonyms	Lu AA 21004

Chemical Properties

Molecular Weight	298.45
Formula	C₁₈H₂₂N₂S
Cas No.	508233-74-7
Smiles	S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3
Relative Density.	1.16 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 200 mM, Sonication is recommended.

DMSO: 20 mg/mL (67.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.7 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	3.3506 mL	16.7532 mL	33.5064 mL	167.5322 mL
5 mM	0.6701 mL	3.3506 mL	6.7013 mL	33.5064 mL
10 mM	0.3351 mL	1.6753 mL	3.3506 mL	16.7532 mL
20 mM	0.1675 mL	0.8377 mL	1.6753 mL	8.3766 mL
50 mM	0.0670 mL	0.3351 mL	0.6701 mL	3.3506 mL

Ethanol

	1mg	5mg	10mg	50mg
100 mM	0.0335 mL	0.1675 mL	0.3351 mL	1.6753 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc