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Sulfamerazine

Name: ROR1 Protein, Human, Recombinant (aa 453-783, His & GST)
Brand: TargetMol
SKU: TMPY-04428
Rating: 4.5 (1 reviews)

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Catalog No. T0913Cas No. 127-79-7

Alias RP2632

Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.

Sulfamerazine

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Purity: 99.78%

Catalog No. T0913Alias RP2632Cas No. 127-79-7

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$30	In Stock	In Stock
500 mg	$58	In Stock	In Stock
1 g	$97	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.78%

Resource Download

COA LCMS HPLC HNMR

Product Introduction

Bioactivity

Description	Sulfamerazine (RP2632) is a long-acting sulfanilamide antibacterial agent. Sulfamerazine inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
In vitro	Sulfamerazine significantly affects the lifespan of rats, markedly prolonging the life of male hamsters. The maximum body weight of all rats fed with sulfamerazine exceeded that of the control group. After oral administration of sulfamerazine, significant alterations in the shape of the concentration-time curve due to age were observed, strongly indicating absorption deficiencies within the first week after birth in lambs.
In vivo	Sulfamerazine exhibits a bi-exponential decay in water and a tri-exponential decay in cyclodextrin (CD) solutions. The resonance of aromatic protons in Sulfamerazine indicates a significant upfield shift, suggesting that the aniline ring is deeply encapsulated within the CD cavity.
Synonyms	RP2632

Chemical Properties

Molecular Weight	264.30
Formula	C₁₁H₁₂N₄O₂S
Cas No.	127-79-7
Smiles	CC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1
Relative Density.	1.439 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (227.01 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.57 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7836 mL	18.9179 mL	37.8358 mL	189.1790 mL
5 mM	0.7567 mL	3.7836 mL	7.5672 mL	37.8358 mL
10 mM	0.3784 mL	1.8918 mL	3.7836 mL	18.9179 mL
20 mM	0.1892 mL	0.9459 mL	1.8918 mL	9.4589 mL
50 mM	0.0757 mL	0.3784 mL	0.7567 mL	3.7836 mL
100 mM	0.0378 mL	0.1892 mL	0.3784 mL	1.8918 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc