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Hydroxytacrine maleate

Name: Hydroxytacrine maleate
Brand: TargetMol
SKU: T21556
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21556Cas No. 118909-22-1

Alias Velnacrine maleate, HP 029 maleate

Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT).

Hydroxytacrine maleate

🥰Excellent

Purity: 98.84%

Catalog No. T21556Alias Velnacrine maleate, HP 029 maleateCas No. 118909-22-1

Pack Size	Price	Availability
25 mg	$30	In Stock
50 mg	$48	In Stock
100 mg	$79	In Stock

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Batch Information

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Purity:98.84%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT).
Synonyms	Velnacrine maleate, HP 029 maleate

Chemical Properties

Molecular Weight	330.34
Formula	C₁₇H₁₈N₂O₅
Cas No.	118909-22-1
Smiles	C(=C\C(O)=O)\C(O)=O.NC1=C2C(=NC=3C1=CC=CC3)CCCC2O
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 20 mg/mL (60.54 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0272 mL	15.1359 mL	30.2718 mL	151.3592 mL
5 mM	0.6054 mL	3.0272 mL	6.0544 mL	30.2718 mL
10 mM	0.3027 mL	1.5136 mL	3.0272 mL	15.1359 mL
20 mM	0.1514 mL	0.7568 mL	1.5136 mL	7.5680 mL
50 mM	0.0605 mL	0.3027 mL	0.6054 mL	3.0272 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc