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Quercetin-3-O-glucose-6''-acetate

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Catalog No. TN2126Cas No. 54542-51-7
Alias 6"-O-Acetylisoquercitrin

Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.

Quercetin-3-O-glucose-6''-acetate

Quercetin-3-O-glucose-6''-acetate

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Purity: 97.48%
Catalog No. TN2126Alias 6"-O-AcetylisoquercitrinCas No. 54542-51-7
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$106-In Stock
5 mg$257-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.48%
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COA HPLC

Product Introduction

Bioactivity
Description
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) is an inhibitor of NADPH oxidase. Quercetin-3-O-glucose-6''-acetate has antioxidant activities.
In vitro
The mulberry leaf contains 4 flavonols in the following order: quercetin-3-β-D-glucose (QT-G) > quercetin-3-O-glucose-6'-acetate (QT-GA) > rutin (RT) > quercetin (QT). In the oxygen radical absorbance capacity (ORAC) assay, QT had the highest peroxyl radical-scavenging capacity and a similar hydroxyl radical-scavenging capacity as its glycosides (QT-G, QT-GA, and RT)[1].
Synonyms6"-O-Acetylisoquercitrin
Chemical Properties
Molecular Weight506.41
FormulaC23H22O13
Cas No.54542-51-7
SmilesO(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2)C3=CC(O)=C(O)C=C3)[C@@H]4O[C@H](COC(C)=O)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.1.77 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (197.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9747 mL9.8734 mL19.7468 mL98.7342 mL
5 mM0.3949 mL1.9747 mL3.9494 mL19.7468 mL
10 mM0.1975 mL0.9873 mL1.9747 mL9.8734 mL
20 mM0.0987 mL0.4937 mL0.9873 mL4.9367 mL
50 mM0.0395 mL0.1975 mL0.3949 mL1.9747 mL
100 mM0.0197 mL0.0987 mL0.1975 mL0.9873 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ROSQuercetin3Oglucose6''acetateQuercetin-3-O-glucose-6''-acetateQuercetin 3 O glucose 6'' acetateNADPH-oxidaseNADPHoxidaseNADPH oxidase
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