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Eldacimibe

Name: Eldacimibe
Brand: TargetMol
SKU: T31611
Price: 146 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T31611Cas No. 141993-70-6

Alias WAY-ACA-147, UNII-4PBL76O2G8, ACA 147

Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.

Eldacimibe

🥰Excellent

Purity: 97.82%

Catalog No. T31611Alias WAY-ACA-147, UNII-4PBL76O2G8, ACA 147Cas No. 141993-70-6

Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.

Pack Size	Price	Availability
1 mg	$146	In Stock
5 mg	$350	In Stock
10 mg	$530	In Stock
25 mg	$859	In Stock
50 mg	$1,180	In Stock
100 mg	$1,590	In Stock
500 mg	$3,190	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:97.82%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.
Synonyms	WAY-ACA-147, UNII-4PBL76O2G8, ACA 147

Chemical Properties

Molecular Weight	634.89
Formula	C₃₉H₅₈N₂O₅
Cas No.	141993-70-6
Smiles	C(N(CC1=CC=C(CC(C)(C)C)C=C1)CCCCCC)(NC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)=C3C(=O)OC(C)(C)OC3=O
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (78.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5751 mL	7.8754 mL	15.7508 mL	78.7538 mL
5 mM	0.3150 mL	1.5751 mL	3.1502 mL	15.7508 mL
10 mM	0.1575 mL	0.7875 mL	1.5751 mL	7.8754 mL
20 mM	0.0788 mL	0.3938 mL	0.7875 mL	3.9377 mL
50 mM	0.0315 mL	0.1575 mL	0.3150 mL	1.5751 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc