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Tricaine methanesulfonate

Name: Tricaine methanesulfonate
Brand: TargetMol
SKU: T21483
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T21483Cas No. 886-86-2

Alias MS-222

Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.

Tricaine methanesulfonate

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Purity: 99.86%

Catalog No. T21483Alias MS-222Cas No. 886-86-2

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 g	$54	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Tricaine methanesulfonate (MS-222) (TMS) is an anesthetic. Many hatcheries and research studies use TMS to immobilize fish for marking or transport and to suppress sensory systems during invasive procedures.
In vitro	Tricaine methanesulfonate in powder form easily can become airborne and may be hazardous to the handler. Tricaine methanesulfonate (TMS) solution is photosensitive (its color changes with light exposure). However, the color change should not be used to gauge degradation due to the color does not necessarily indicate significant activity decrease.
Synonyms	MS-222

Chemical Properties

Molecular Weight	261.30
Formula	C₁₀H₁₅NO₅S
Cas No.	886-86-2
Smiles	CCOC(c1cc(N)ccc1)=O.CS(O)(=O)=O
Relative Density.	1.3799 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 255 mg/mL (975.89 mM)

H2O: 249 mg/mL (952.93 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8270 mL	19.1351 mL	38.2702 mL	191.3509 mL
5 mM	0.7654 mL	3.8270 mL	7.6540 mL	38.2702 mL
10 mM	0.3827 mL	1.9135 mL	3.8270 mL	19.1351 mL
20 mM	0.1914 mL	0.9568 mL	1.9135 mL	9.5675 mL
50 mM	0.0765 mL	0.3827 mL	0.7654 mL	3.8270 mL
100 mM	0.0383 mL	0.1914 mL	0.3827 mL	1.9135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc