Shopping Cart

Your shopping cart is currently empty

Etebenecid

Name: Etebenecid
Brand: TargetMol
SKU: T15251
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T15251Cas No. 1213-06-5

Alias Urelim

Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.

Etebenecid

Copy Product Info

😃Good

Purity: 99.99%

Catalog No. T15251Alias UrelimCas No. 1213-06-5

Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$30	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.99%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Etebenecid AI Summary

Etebenecid exhibits diverse bioactivities including the inhibition of ELG1-dependent DNA repair in human embryonic kidney cells and the formation of the Importin beta complex. It also serves as a delayed death inhibitor for the malarial parasite plastid, inhibits Polymerase Iota, and induces DNA re-replication in SW480 colon adenocarcinoma cells. Furthermore, it acts as an agonist of gsp, responsible for Etiologic Mutation in Fibrous Dysplasia/McCune-Albright Syndrome, and blocks Ebola Virus entry in various screening assays. Additionally, it demonstrates antiviral properties, inhibiting SARS-CoV-2-induced cytotoxicity in both Caco-2 and VERO-6 cells at a concentration of 10 µM after 48 hours, with inhibition rates of 10.35% and 0.06%, respectively. Moreover, Etebenecid inhibits the SARS-CoV-2 3CL-Pro protease by 7.847% at 20 µM, and it inhibits human HDAC6 activity, with varied inhibition rates depending on the peptide substrate used..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Etebenecid (Urelim) is uricosuric agents, which lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys. It also inhibits penicillin tubular secretion.
Synonyms	Urelim

Chemical Properties

Molecular Weight	257.31
Formula	C₁₁H₁₅NO₄S
Cas No.	1213-06-5
Smiles	CCN(CC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
Relative Density.	1.283 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 249 mg/mL (967.7 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (19.43 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8864 mL	19.4318 mL	38.8636 mL	194.3181 mL
5 mM	0.7773 mL	3.8864 mL	7.7727 mL	38.8636 mL
10 mM	0.3886 mL	1.9432 mL	3.8864 mL	19.4318 mL
20 mM	0.1943 mL	0.9716 mL	1.9432 mL	9.7159 mL
50 mM	0.0777 mL	0.3886 mL	0.7773 mL	3.8864 mL
100 mM	0.0389 mL	0.1943 mL	0.3886 mL	1.9432 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc