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S-Adenosyl-L-methionine

Name: S-Adenosyl-L-methionine
Brand: TargetMol
SKU: T7475
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7475Cas No. 29908-03-0

Alias SAMe, S-Adenosyl methionine, AdoMet, Ademetionine

S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.

S-Adenosyl-L-methionine

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Purity: 99.08%

Catalog No. T7475Alias SAMe, S-Adenosyl methionine, AdoMet, AdemetionineCas No. 29908-03-0

S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$34	-	In Stock
5 mg	$72	Inquiry	Inquiry
10 mg	$98	Inquiry	Inquiry
25 mg	$168	Inquiry	Inquiry
50 mg	$248	Inquiry	Inquiry
100 mg	$369	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.08%

Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
Synonyms	SAMe, S-Adenosyl methionine, AdoMet, Ademetionine

Chemical Properties

Molecular Weight	398.44
Formula	C₁₅H₂₂N₆O₅S
Cas No.	29908-03-0
Smiles	C[S+](CC[C@H](N)C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Relative Density.	no data available

Storage & Solubility Information

Storage

store under nitrogen,store at low temperature,keep away from moisture | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 43 mg/mL (107.92 mM), Sonication is recommended.

DMSO: 100 mg/mL (250.98 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5098 mL	12.5489 mL	25.0979 mL	125.4894 mL
5 mM	0.5020 mL	2.5098 mL	5.0196 mL	25.0979 mL
10 mM	0.2510 mL	1.2549 mL	2.5098 mL	12.5489 mL
20 mM	0.1255 mL	0.6274 mL	1.2549 mL	6.2745 mL
50 mM	0.0502 mL	0.2510 mL	0.5020 mL	2.5098 mL
100 mM	0.0251 mL	0.1255 mL	0.2510 mL	1.2549 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc