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SLIGRL-NH2

Name: SLIGRL-NH2
Brand: TargetMol
SKU: TP1046
Rating: 4.5 (1 reviews)

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Catalog No. TP1046Cas No. 171436-38-7

Alias Protease-Activated Receptor-2 Activating Peptide

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.

SLIGRL-NH2

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Purity: 98.29%

Catalog No. TP1046Alias Protease-Activated Receptor-2 Activating PeptideCas No. 171436-38-7

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$99	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.29%

Resource Download

COA LCMS

Product Introduction

Bioactivity

Description	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is a PAR-2 agonist that induces non-histaminergic pruritus.
Synonyms	Protease-Activated Receptor-2 Activating Peptide

Chemical Properties

Molecular Weight	656.82
Formula	C₂₉H₅₆N₁₀O₇
Cas No.	171436-38-7
Smiles	CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O
Relative Density.	1.342g/cm3
Color	White
Appearance	Solid
Sequence	Ser-Leu-Ile-Gly-Arg-Leu-NH2
Sequence Short	SLIGRL-NH2

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (121.80 mM), Sonication is recommended.

H2O: 80 mg/mL (121.8 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.5225 mL	7.6124 mL	15.2249 mL	76.1244 mL
5 mM	0.3045 mL	1.5225 mL	3.0450 mL	15.2249 mL
10 mM	0.1522 mL	0.7612 mL	1.5225 mL	7.6124 mL
20 mM	0.0761 mL	0.3806 mL	0.7612 mL	3.8062 mL
50 mM	0.0304 mL	0.1522 mL	0.3045 mL	1.5225 mL
100 mM	0.0152 mL	0.0761 mL	0.1522 mL	0.7612 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc