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6-Methyl-5-azacytidine

Name: 6-Methyl-5-azacytidine
Brand: TargetMol
SKU: T10184
Rating: 4.5 (1 reviews)

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Catalog No. T10184Cas No. 105330-94-7

6-Methyl-5-azacytidine is a potent DNMT (DNA methyltransferase) inhibitor.

6-Methyl-5-azacytidine

😃Good

Catalog No. T10184Cas No. 105330-94-7

6-Methyl-5-azacytidine is a potent DNMT (DNA methyltransferase) inhibitor.

Pack Size	Price	Availability
25 mg	$1,520	3-6 months
50 mg	$1,980	3-6 months
100 mg	$2,500	3-6 months

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description

6-Methyl-5-azacytidine is a potent DNMT (DNA methyltransferase) inhibitor.

Chemical Properties

Molecular Weight	258.23
Formula	C₉H₁₄N₄O₅
Cas No.	105330-94-7
Relative Density.	1.95 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (484.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8725 mL	19.3626 mL	38.7252 mL	193.6258 mL
5 mM	0.7745 mL	3.8725 mL	7.7450 mL	38.7252 mL
10 mM	0.3873 mL	1.9363 mL	3.8725 mL	19.3626 mL
20 mM	0.1936 mL	0.9681 mL	1.9363 mL	9.6813 mL
50 mM	0.0775 mL	0.3873 mL	0.7745 mL	3.8725 mL
100 mM	0.0387 mL	0.1936 mL	0.3873 mL	1.9363 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc