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Z62954982

Name: Z62954982
Brand: TargetMol
SKU: T37113
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T37113Cas No. 1090893-12-1

Alias ZINC08010136

Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.

Z62954982

🥰Excellent

Purity: 98.28%

Catalog No. T37113Alias ZINC08010136Cas No. 1090893-12-1

Pack Size	Price	Availability
1 mg	$32	In Stock
5 mg	$73	In Stock
10 mg	$113	In Stock
25 mg	$193	In Stock
50 mg	$283	In Stock
100 mg	$413	In Stock
200 mg	$589	In Stock
1 mL x 10 mM (in DMSO)	$84	In Stock

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Batch Information

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Purity:98.28%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.
Synonyms	ZINC08010136

Chemical Properties

Molecular Weight	415.46
Formula	C₂₀H₂₁N₃O₅S
Cas No.	1090893-12-1
Smiles	O=C(NC1=CC=C(C(=C1)S(=O)(=O)N)C)C=2C=CC=C(OCC=3C(=NOC3C)C)C2
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (24.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4070 mL	12.0349 mL	24.0697 mL	120.3485 mL
5 mM	0.4814 mL	2.4070 mL	4.8139 mL	24.0697 mL
10 mM	0.2407 mL	1.2035 mL	2.4070 mL	12.0349 mL
20 mM	0.1203 mL	0.6017 mL	1.2035 mL	6.0174 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc