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Z62954982

Catalog No. T37113 CAS 1090893-12-1

Synonyms: ZINC08010136

Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.CAS 번호134607-86-5

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Z62954982, CAS 1090893-12-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 38.00
5 mg	In stock	$ 82.00
10 mg	In stock	$ 118.00
25 mg	In stock	$ 193.00
50 mg	In stock	$ 286.00
100 mg	In stock	$ 423.00
1 mL * 10 mM (in DMSO)	In stock	$ 100.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	ZINC08010136
Molecular Weight	415.46
Formula	C20H21N3O5S
CAS No.	1090893-12-1

Storage

store at low temperature

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mg/mL (24.07 mM), Sonication is recommended.

References and Literature

1. Gokoffski KK,et al. Physiologic Electrical Fields Direct Retinal Ganglion Cell Axon Growth In Vitro. Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3659-3668. 2. Yan Y,et al. Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching. Cereb Cortex. 2015 Oct;25(10):3487-501. 3. Zhang XE,et al. Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. PLoS One. 2016 May 17;11(5):e0155490.

Related Products

Related compounds with same targets

Digeranyl bisphosphonate Rac1 Inhibitor W56 acetate(1095179-01-3 free base) SKLB-163 SAR407899 EHT 1864 ZINC69391 AZA1 MLS000532223

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Z62954982 1090893-12-1 Cell Cycle/Checkpoint Rho Z-62954982 Z 62954982 ZINC08010136 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.