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Sotevtamab

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Catalog No. T76994Cas No. 2411526-47-9
Alias AB-16B5, AB16B5, 16B5

Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an epithelial-mesenchymal transition inhibitor with antitumor activity, used in studies of colorectal cancer.

Sotevtamab

Sotevtamab

😃Good
Catalog No. T76994Alias AB-16B5, AB16B5, 16B5Cas No. 2411526-47-9
Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an epithelial-mesenchymal transition inhibitor with antitumor activity, used in studies of colorectal cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$247In StockIn Stock
5 mg$645In StockIn Stock
10 mg$987-In Stock
25 mg$1,530-In Stock
50 mg$1,980-In Stock
100 mg$2,790-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:95.8% (SDS-PAGE); 100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an epithelial-mesenchymal transition inhibitor with antitumor activity, used in studies of colorectal cancer.
In vivo
Sotevtamab (5 mg/kg twice weekly) was able to inhibit tumor growth in mice with prostate and breast cancer. [1]
SynonymsAB-16B5, AB16B5, 16B5
Reactivity
Human
Verified Activity
Immobilized Human Clusterin Protein (Fc) at 2 μg/mL (30 μL/well) can bind Sotevtamab (AB-16B5). The EC50 is 27.35 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetClusterin
Chemical Properties
Molecular Weight146.2 kDa
Cas No.2411526-47-9
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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