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Sotevtamab
(Synonyms: AB-16B5, AB16B5, 16B5) Copy Product Info
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Synonyms: AB-16B5, AB16B5, 16B5
Catalog No. T76994 Copy Product Info
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Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an epithelial-mesenchymal transition inhibitor with antitumor activity, used in studies of colorectal cancer.
Sotevtamab
Cas No. 2411526-47-9
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | In Stock | In Stock | |
| 5 mg | $645 | In Stock | In Stock | |
| 10 mg | $987 | - | In Stock | |
| 25 mg | $1,530 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock | |
| 100 mg | $2,790 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.8% (SDS-PAGE); 100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
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| Description | Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an epithelial-mesenchymal transition inhibitor with antitumor activity, used in studies of colorectal cancer. |
| In vivo | Sotevtamab (5 mg/kg twice weekly) was able to inhibit tumor growth in mice with prostate and breast cancer. [1] |
| Synonyms | AB-16B5, AB16B5, 16B5 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Clusterin Protein (Fc) at 2 μg/mL (30 μL/well) can bind Sotevtamab (AB-16B5). The EC50 is 27.35 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Clusterin |
| Molecular Weight | 146.2 kDa |
| Cas No. | 2411526-47-9 |
| Isotype | Human IgG2 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Sotevtamab in vivo | Sotevtamab molecular weight
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