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Hexadimethrine bromide

Name: Hexadimethrine bromide
Brand: TargetMol
SKU: T13720
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13720Cas No. 28728-55-4

Alias Polybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide

Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.

Hexadimethrine bromide

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Purity: 99.18%

Catalog No. T13720Alias Polybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromideCas No. 28728-55-4

Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$41	-	In Stock
100 mg	$66	In Stock	In Stock
200 mg	$94	-	In Stock
500 mg	$158	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.18%

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COA LCMS

Product Introduction

Bioactivity

Description	Hexadimethrine bromide (1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide) is a synthetic polymer which agglutinates red blood cells, and used as a heparin antagonist.
In vitro	Hexadimethrine bromide impedes the proliferation of human mesenchymal stem cells during lentiviral transduction and is deemed non-toxic at low concentrations. Yet, at levels exceeding 10 µg/mL, it adversely impacts the proliferation of certain cell types. Moreover, cells treated with Hexadimethrine bromide and then trypsinized appear significantly enlarged under microscopic examination.
Synonyms	Polybrene, 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide

Chemical Properties

Molecular Weight	404.275
Formula	(C₁₃H₃₀N₂)n.Br₂
Cas No.	28728-55-4
Smiles	[Br-].[Br-].CCCCCCC[N+](C)(C)CCC[N+](C)(C)C
Relative Density.	no data available
Color	White
Appearance	Viscous

Storage & Solubility Information

Storage

keep away from moisture,store under nitrogen | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4.50 mg/mL (11.13 mM), Sonication and heating are recommended.

H2O: 125.00 mg/mL (309.20 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	2.4736 mL	12.3678 mL	24.7356 mL	123.6782 mL
5 mM	0.4947 mL	2.4736 mL	4.9471 mL	24.7356 mL
10 mM	0.2474 mL	1.2368 mL	2.4736 mL	12.3678 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.1237 mL	0.6184 mL	1.2368 mL	6.1839 mL
50 mM	0.0495 mL	0.2474 mL	0.4947 mL	2.4736 mL
100 mM	0.0247 mL	0.1237 mL	0.2474 mL	1.2368 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

InhibitorinhibitHexadimethrine bromideHexadimethrineheparin