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Anti-Monkey/Human CD40L/CD154 Antibody (5C8)

Catalog No. T9901A-532 Copy Product Info
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Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse inhibitory antibody targeting monkey/human CD40L/CD154, blocking the interaction between CD154 and CD40. It can be used in inflammation and immunology-related research, including colitis and transplantation studies.

Anti-Monkey/Human CD40L/CD154 Antibody (5C8)

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Catalog No. T9901A-532

Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse inhibitory antibody targeting monkey/human CD40L/CD154, blocking the interaction between CD154 and CD40. It can be used in inflammation and immunology-related research, including colitis and transplantation studies.

Anti-Monkey/Human CD40L/CD154 Antibody
(5C8)
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$2972-4 weeks2-4 weeks
5 mg$8982-4 weeks2-4 weeks
10 mg$1,4302-4 weeks2-4 weeks
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse inhibitory antibody targeting monkey/human CD40L/CD154, blocking the interaction between CD154 and CD40. It can be used in inflammation and immunology-related research, including colitis and transplantation studies.
In vitro
Anti-Monkey/Human CD40L/CD154 Antibody (5C8) can inhibit the mixed lymphocyte reaction of rhesus monkeys within the concentration range of 0.01–100 μg/mL [1].
In vivo
Anti-Monkey/Human CD40L/CD154 Antibody (5C8), administered intravenously at a dose of 20 mg/kg once every two days for 14 consecutive days, can inhibit allogeneic renal transplant rejection in a mouse model of renal transplantation [1].
When administered intraperitoneally at a dose of 250 μg per mouse twice a week for 8 consecutive weeks, Anti-Monkey/Human CD40L/CD154 Antibody (5C8) can prevent the occurrence of experimental colitis and alleviate the condition in a mouse model reconstituted with CD45RBhigh CD4+ T cells [2].
Clone
5C8
Reactivity
Human/Monkey
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetTNFSF5/CD40L/CD154
Chemical Properties
Molecular Weight150 kDa
Antibody Information
IsotypeMouse IgG2a
Recommended Isotype Control
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice.

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