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Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse inhibitory antibody targeting monkey/human CD40L/CD154, blocking the interaction between CD154 and CD40. It can be used in inflammation and immunology-related research, including colitis and transplantation studies.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $297 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $898 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $1,430 | 2-4 weeks | 2-4 weeks |
| Description | Anti-Monkey/Human CD40L/CD154 Antibody (5C8) is a mouse inhibitory antibody targeting monkey/human CD40L/CD154, blocking the interaction between CD154 and CD40. It can be used in inflammation and immunology-related research, including colitis and transplantation studies. |
| In vitro | Anti-Monkey/Human CD40L/CD154 Antibody (5C8) can inhibit the mixed lymphocyte reaction of rhesus monkeys within the concentration range of 0.01–100 μg/mL [1]. |
| In vivo | Anti-Monkey/Human CD40L/CD154 Antibody (5C8), administered intravenously at a dose of 20 mg/kg once every two days for 14 consecutive days, can inhibit allogeneic renal transplant rejection in a mouse model of renal transplantation [1]. When administered intraperitoneally at a dose of 250 μg per mouse twice a week for 8 consecutive weeks, Anti-Monkey/Human CD40L/CD154 Antibody (5C8) can prevent the occurrence of experimental colitis and alleviate the condition in a mouse model reconstituted with CD45RBhigh CD4+ T cells [2]. |
| Clone | 5C8 |
| Reactivity | Human/Monkey |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | TNFSF5/CD40L/CD154 |
| Molecular Weight | 150 kDa |
| Isotype | Mouse IgG2a |
| Recommended Isotype Control |
| Storage | Store at -20°C Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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