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BZAD01

Name: BZAD01
Brand: TargetMol
SKU: T25196
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T25196Cas No. 305339-41-7

Alias BZAD-01, BZAD 01

BZAD01 is a selective NMDA NR1A/2B receptor antagonist.

BZAD01

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Purity: 99.70%

Catalog No. T25196Alias BZAD-01, BZAD 01Cas No. 305339-41-7

BZAD01 is a selective NMDA NR1A/2B receptor antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$32	In Stock	In Stock
10 mg	$53	In Stock	In Stock
25 mg	$107	In Stock	In Stock
50 mg	$167	In Stock	In Stock
100 mg	$277	In Stock	In Stock
200 mg	$386	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.70%

Appearance:Solid

Color:White

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COA LCMS

Product Introduction

Bioactivity

Description	BZAD01 is a selective NMDA NR1A/2B receptor antagonist.
In vivo	Parkinsonism was induced by microinjection of the toxin, 6-hydroxydopamine (6-OHDA) into the medial forebrain bundle (MFB) of 40 Sprague-Dawley rats. Parkinsonism and the efficacy of drugs were assessed using a battery of behavioural tests including balance beam, apomorphine-induced rotation, body axis bias or "curling", head position bias and disengage sensorimotor latency test. The main effects were that BZAD01 co-administration prevented chronic levodopa-induced potentiation of apomorphine rotation. However levodopa-treated rats were slower than either controls or BZAD-01-treated rats in the locomotor test[2].
Synonyms	BZAD-01, BZAD 01

Chemical Properties

Molecular Weight	362.27
Formula	C₁₆H₁₂F₆N₂O
Cas No.	305339-41-7
Smiles	FC(F)(F)Oc1ccc(cc1)C(=N)NCc1ccccc1C(F)(F)F
Relative Density.	1.34 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (151.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7604 mL	13.8019 mL	27.6037 mL	138.0186 mL
5 mM	0.5521 mL	2.7604 mL	5.5207 mL	27.6037 mL
10 mM	0.2760 mL	1.3802 mL	2.7604 mL	13.8019 mL
20 mM	0.1380 mL	0.6901 mL	1.3802 mL	6.9009 mL
50 mM	0.0552 mL	0.2760 mL	0.5521 mL	2.7604 mL
100 mM	0.0276 mL	0.1380 mL	0.2760 mL	1.3802 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc