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Tectol

Name: Tectol
Brand: TargetMol
SKU: TN6512
Price: 109 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. TN6512Cas No. 24449-39-6

Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.

Tectol

🥰Excellent

Purity: 99.23%

Catalog No. TN6512Cas No. 24449-39-6

Pack Size	Price	Availability
1 mg	$109	In Stock
5 mg	$233	In Stock
10 mg	$347	In Stock
25 mg	$579	In Stock
1 mL x 10 mM (in DMSO)	$268	In Stock

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Purity:99.23%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
Targets&IC50	FTase:3.44±0.20μM
In vitro	Eleven known compounds and a new prenylated naphthoquinone, lippsidoquinone , were isolated from ethanol extracts of Lippia sidoides. Their structures were established by a combination of 1D and 2D NMR, IR, and EIMS spectral data analysis. The cytotoxic properties of compounds 3--13 were evaluated against HL60, SW1573, and CEM cell lines. Only Tectol and lippsidoquinone exhibited significant activity against human leukemia cell lines HL60 and CEM[1].

Chemical Properties

Molecular Weight	450.52
Formula	C₃₀H₂₆O₄
Cas No.	24449-39-6
Smiles	CC1(C)Oc2c(C=C1)c(c(O)c1ccccc21)-c1c(O)c2ccccc2c2OC(C)(C)C=Cc12
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (122.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2197 mL	11.0983 mL	22.1966 mL	110.9829 mL
5 mM	0.4439 mL	2.2197 mL	4.4393 mL	22.1966 mL
10 mM	0.2220 mL	1.1098 mL	2.2197 mL	11.0983 mL
20 mM	0.1110 mL	0.5549 mL	1.1098 mL	5.5491 mL
50 mM	0.0444 mL	0.2220 mL	0.4439 mL	2.2197 mL
100 mM	0.0222 mL	0.1110 mL	0.2220 mL	1.1098 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc