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U 19963

Name: U 19963
Brand: TargetMol
SKU: T4177
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T4177Cas No. 404-52-4

U 19963 is a potent inhibitor of several enzymes and receptors and has been used to study the effects of drugs on biological systems. It has been found to possess a wide range of biological activities, including anti-inflammatory, anti-tumor and antibacterial properties.

U 19963

🥰Excellent

Purity: 99.94%

Catalog No. T4177Cas No. 404-52-4

Pack Size	Price	Availability
5 mg	$41	In Stock
10 mg	$53	In Stock
25 mg	$102	In Stock
50 mg	$151	In Stock
100 mg	$225	In Stock
200 mg	$323	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.94%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	264.29
Formula	C₁₃H₁₀F₂N₂S
Cas No.	404-52-4
Smiles	N(C(NC1=CC=C(F)C=C1)=S)C2=CC=C(F)C=C2
Relative Density.	1.419 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (208.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7837 mL	18.9186 mL	37.8372 mL	189.1861 mL
5 mM	0.7567 mL	3.7837 mL	7.5674 mL	37.8372 mL
10 mM	0.3784 mL	1.8919 mL	3.7837 mL	18.9186 mL
20 mM	0.1892 mL	0.9459 mL	1.8919 mL	9.4593 mL
50 mM	0.0757 mL	0.3784 mL	0.7567 mL	3.7837 mL
100 mM	0.0378 mL	0.1892 mL	0.3784 mL	1.8919 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc