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Amicarbazone
😃Good
Catalog No. T14218Cas No. 129909-90-6
Alias BAY-MKH 3586, BAY314666
Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive plants. Despite these severe effects, it exhibits good selectivity and outperforms atrazine as a herbicide, allowing for its application at lower doses compared to traditional photosynthetic inhibitors.
Amicarbazone
😃Good
Catalog No. T14218Alias BAY-MKH 3586, BAY314666Cas No. 129909-90-6
Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive plants. Despite these severe effects, it exhibits good selectivity and outperforms atrazine as a herbicide, allowing for its application at lower doses compared to traditional photosynthetic inhibitors.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $30 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Amicarbazone (BAY-MKH3586; BAY314666) is a potent PSII inhibitor, disrupting photosynthetic electron transport by binding to the Qb domain of photosystem II. This broad-spectrum herbicide is effective through foliar and root application, showcasing rapid absorption and translocation. However, its effectiveness can be compromised by common PSII inhibitor resistance. With an IC50 value indicating high potency, amicarbazone leads to chlorosis, stunted growth, tissue necrosis, and death in sensitive plants. Despite these severe effects, it exhibits good selectivity and outperforms atrazine as a herbicide, allowing for its application at lower doses compared to traditional photosynthetic inhibitors. |
| Synonyms | BAY-MKH 3586, BAY314666 |
| Molecular Weight | 241.29 |
| Formula | C10H19N5O2 |
| Cas No. | 129909-90-6 |
| Smiles | CC(C)c1nn(C(=O)NC(C)(C)C)c(=O)n1N |
| Relative Density. | 1.12 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | H2O: 1 mg/mL (4.14 mM), Sonication and heating to 50℃ are recommended. | ||||||||||
Solution Preparation Table | |||||||||||
H2O
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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