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α-Angelica lactone

Name: α-Angelica lactone
Brand: TargetMol
SKU: T7995
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7995Cas No. 591-12-8

Alias Alpha-Angelica Lactone

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

α-Angelica lactone

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Purity: 99.79%

Catalog No. T7995Alias Alpha-Angelica LactoneCas No. 591-12-8

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.79%

Appearance:Liquid

Color:Transparent

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.
In vivo	α-angelicalactone, inhibited benzo(a)pyrene-induced neoplasia of the mouse forestomach and was more potent in this regard than coumarin.
Synonyms	Alpha-Angelica Lactone

Chemical Properties

Molecular Weight	98.1
Formula	C₅H₆O₂
Cas No.	591-12-8
Smiles	CC=1OC(=O)CC1
Relative Density.	1.092

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (229.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (20.39 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	10.1937 mL	50.9684 mL	101.9368 mL	509.6840 mL
5 mM	2.0387 mL	10.1937 mL	20.3874 mL	101.9368 mL
10 mM	1.0194 mL	5.0968 mL	10.1937 mL	50.9684 mL
20 mM	0.5097 mL	2.5484 mL	5.0968 mL	25.4842 mL
50 mM	0.2039 mL	1.0194 mL	2.0387 mL	10.1937 mL
100 mM	0.1019 mL	0.5097 mL	1.0194 mL	5.0968 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc