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α-Angelica lactone

Name: α-Angelica lactone
Brand: TargetMol
SKU: T7995
Rating: 4.5 (1 reviews)

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Catalog No. T7995Cas No. 591-12-8

Alias Alpha-Angelica Lactone

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

α-Angelica lactone

😃Good

Catalog No. T7995Alias Alpha-Angelica LactoneCas No. 591-12-8

α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$29	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.
In vivo	α-angelicalactone, inhibited benzo(a)pyrene-induced neoplasia of the mouse forestomach and was more potent in this regard than coumarin.
Synonyms	Alpha-Angelica Lactone

Chemical Properties

Molecular Weight	98.1
Formula	C₅H₆O₂
Cas No.	591-12-8
Smiles	CC=1OC(=O)CC1
Relative Density.	1.092

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (229.36 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (20.39 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	10.1937 mL	50.9684 mL	101.9368 mL	509.6840 mL
5 mM	2.0387 mL	10.1937 mL	20.3874 mL	101.9368 mL
10 mM	1.0194 mL	5.0968 mL	10.1937 mL	50.9684 mL
20 mM	0.5097 mL	2.5484 mL	5.0968 mL	25.4842 mL
50 mM	0.2039 mL	1.0194 mL	2.0387 mL	10.1937 mL
100 mM	0.1019 mL	0.5097 mL	1.0194 mL	5.0968 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc