Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 193.00 | |
25 mg | In stock | $ 413.00 | |
50 mg | In stock | $ 615.00 | |
100 mg | In stock | $ 876.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM. |
Targets&IC50 | Proliferation (T-cells):~5 μM |
Molecular Weight | 252.33 |
Formula | C15H12N2S |
CAS No. | 79220-94-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 25.23 mg/mL (100 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KRM-III 79220-94-3 Others KRMIII KRM III inhibitor inhibit