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OGT inhibitor 4a

Name: OGT inhibitor 4a
Brand: TargetMol
SKU: T88438
Price: 247 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T88438 Copy Product Info

Purity: 99.08%

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OGT inhibitor 4a is an O-linked n-acetylglucosaminyltransferase (OGT) inhibitor with anticancer activity for the study of autoimmune and neurological disorders.

OGT inhibitor 4a

Copy Product Info

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Catalog No. T88438

OGT inhibitor 4a is an O-linked n-acetylglucosaminyltransferase (OGT) inhibitor with anticancer activity for the study of autoimmune and neurological disorders.

Cas No. 2411972-44-4

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Pack Size	Price	USA Stock	Global Stock
1 mg	$247	In Stock	In Stock
5 mg	$543	In Stock	In Stock
10 mg	$814	In Stock	In Stock
25 mg	$1,380	In Stock	In Stock
50 mg	$2,080	In Stock	In Stock
100 mg	$3,110	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.08%

ee:100%

Appearance:Solid

Color:White

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COA CSFC HNMR LCMS ORP

Product Introduction

Bioactivity

Description	OGT inhibitor 4a is an O-linked n-acetylglucosaminyltransferase (OGT) inhibitor with anticancer activity for the study of autoimmune and neurological disorders.
Targets&IC50	OGT:8 nM (Kd)

Chemical Properties

Molecular Weight	576.04
Formula	C₂₅H₂₂ClN₃O₇S₂
Cas No.	2411972-44-4
Smiles	[C@@H](C(N(CC1=CC=CS1)CC(O)=O)=O)(NS(=O)(=O)C=2C=C3C(=CC2Cl)NC(=O)C=C3)C4=C(OC)C=CC=C4
Relative Density.	no data available

Storage & Solubility Information

Storage

02 | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 237.5 mg/mL (412.3 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7360 mL	8.6800 mL	17.3599 mL	86.7995 mL
5 mM	0.3472 mL	1.7360 mL	3.4720 mL	17.3599 mL
10 mM	0.1736 mL	0.8680 mL	1.7360 mL	8.6800 mL
20 mM	0.0868 mL	0.4340 mL	0.8680 mL	4.3400 mL
50 mM	0.0347 mL	0.1736 mL	0.3472 mL	1.7360 mL
100 mM	0.0174 mL	0.0868 mL	0.1736 mL	0.8680 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc