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Fluridone

Catalog No. T60952 CAS 59756-60-4

Synonyms: EL-171

Fluridone (EL-171) is a potent inhibitor of abscisic acid (ABA) synthesis, inhibits the expression of AchnFAR and TF genes, and reduces the formation of primary alcohol. Fluridone is often used as an aquatic herbicide to control invasive plants and is also used to control species such as hydra and Eurasian hydra.

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Fluridone, CAS 59756-60-4

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 41.00
500 mg	In stock	$ 96.00

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Purity: 97.55%

Biological Description

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Storage & Solubility Information

Description	Fluridone (EL-171) is a potent inhibitor of abscisic acid (ABA) synthesis, inhibits the expression of AchnFAR and TF genes, and reduces the formation of primary alcohol. Fluridone is often used as an aquatic herbicide to control invasive plants and is also used to control species such as hydra and Eurasian hydra.
Targets&IC50	Phytoene desaturase:0.03 μM(ki)
In vitro	Fluridone is cytotoxic to the cyanobacterium Anacystis nidulans (LC50 = 0.125 µM).[1][4] Fluridone (50 and 100 µM) decreases β-carotene levels and induces accumulation of phytofluene and phytoene in T. aestivum seedlings grown in the dark.[2] It reduces levels of the plant hormone abscisic acid in hydrated and dehydrated V. faba leaves when used at a concentration of 10 µM.[3]
In vivo	Fluridone has acute toxicity against several species of invertebrates and fish (median LC50s = 4.3 and 10.4 mg/L, respectively).1,4 Formulations containing fluridone have been used as aquatic herbicides.[1][4]

Synonyms	EL-171
Molecular Weight	329.32
Formula	C19H14F3NO
CAS No.	59756-60-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 225.0 mg/mL (683.2 mM), Sonication and heating to 60℃ are recommended.

References and Literature

1. Chamovitz D, et al. Molecular and biochemical characterization of herbicide-resistant mutants of cyanobacteria reveals that phytoene desaturation is a rate-limiting step in carotenoid biosynthesis. J Biol Chem. 1993;268(23):17348-17353. 2. Bartels P G, et al. Inhibition of carotenoid synthesis by fluridone and norflurazon. Weed Science, 1978;26(2): 198-203. 3. Popova L P, et al. Development and accumulation of ABA in fluridone‐treated and drought‐stressed Vicia faba plants under different light conditions. Physiologia Plantarum, 1996;98(4): 791-797. 4. Hamelink J L, et al. Toxicity of fluridone to aquatic invertebrates and fish[J]. Environmental Toxicology and Chemistry. An International Journal. 1986;5(1): 87-94.

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Keywords

Fluridone 59756-60-4 Others EL-171 EL 171 EL171 inhibitor inhibit

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